Our labs
Clemens Lab
Regina Clemens, MD, PhD
Neutrophils play a key role in host defense and have an ever-expanding list of roles in health and disease. However, neutrophil dysregulation can lead to catastrophic inflammation. In the intensive care unit, neutrophil dysfunction contributes to pathology in many diseases including sepsis, organ transplant, acute lung injury and stroke.
Friess Lab
Stuart Friess, MD
Research in our lab is focused on traumatic brain injury (TBI). Specifically, we are focused on utilizing clinical relevant animal models of TBI to study the effects of secondary insults — intracranial hypertension, hypoxemia and neuroinflammation — after moderate and severe TBI.
Recent publications
- Pediatric Moyamoya Revascularization Perioperative Care: A Modified Delphi StudySun, L. R., Jordan, L. C., Smith, E. R., Aldana, P. R., Kirschen, M. P., Guilliams, K., Gupta, N., Steinberg, G. K., Fox, C., Harrar, D. B., Lee, S., Chung, M. G., Dirks, P., Dlamini, N., Maher, C. O., Lehman, L. L., Hong, S. J., Strahle, J. M., Pineda, J. A., Beslow, L. A., & 11 othersRasmussen, L., Mailo, J., Piatt, J., Lang, S. S., Adelson, P. D., Dewan, M. C., Mineyko, A., McClugage, S., Vadivelu, S., Dowling, M. M. & Hersh, D. S., Apr 2024, In: Neurocritical Care. 40, 2, p. […]
- Fluid assessment, fluid balance, and fluid overload in sick children: a report from the Pediatric Acute Disease Quality Initiative (ADQI) conferenceon behalf of the Pediatric the Acute Disease Quality Initiative (ADQI) Consensus Committee Members, Mar 2024, In: Pediatric Nephrology. 39, 3, p. 955-979 25 p.Research output: Contribution to journal › Article › peer-review
- Epidemiology of acute kidney injury in children: a report from the 26th Acute Disease Quality Initiative (ADQI) consensus conferenceThe ADQI 26 workgroup, Mar 2024, In: Pediatric Nephrology. 39, 3, p. 919-928 10 p.Research output: Contribution to journal › Article › peer-review
- Pediatric AKI in the real world: changing outcomes through education and advocacy—a report from the 26th Acute Disease Quality Initiative (ADQI) consensus conferenceThe ADQI 26 workgroup, Mar 2024, In: Pediatric Nephrology. 39, 3, p. 1005-1014 10 p.Research output: Contribution to journal › Article › peer-review
- Programs and processes for advancing pediatric acute kidney support therapy in hospitalized and critically ill children: a report from the 26th Acute Disease Quality Initiative (ADQI) consensus conferenceThe ADQI 26 workgroup, Mar 2024, In: Pediatric Nephrology. 39, 3, p. 993-1004 12 p.Research output: Contribution to journal › Article › peer-review
- A proposed framework for advancing acute kidney injury risk stratification and diagnosis in children: a report from the 26th Acute Disease Quality Initiative (ADQI) conferenceThe ADQI 26 workgroup, Mar 2024, In: Pediatric Nephrology. 39, 3, p. 929-939 11 p.Research output: Contribution to journal › Article › peer-review
- Major Adverse Kidney Events in Pediatric Continuous Kidney Replacement TherapyFuhrman, D. Y., Stenson, E. K., Alhamoud, I., Alobaidi, R., Bottari, G., Fernandez, S., Guzzi, F., Haga, T., Kaddourah, A., Marinari, E., Mohamed, T. H., Morgan, C. J., Mottes, T., Neumayr, T. M., Ollberding, N. J., Raggi, V., Ricci, Z., See, E., Stanski, N. L., Zang, H., & 2 othersZangla, E. & Gist, K. M., Feb 23 2024, In: JAMA Network Open. 7, 2, p. E240243Research output: Contribution to journal › Article › peer-review
- Intravenous Levothyroxine for Unstable Brain-Dead Heart DonorsMalone, J. R., Feb 8 2024, In: New England Journal of Medicine. 390, 6, p. 574-576 3 p.Research output: Contribution to journal › Letter › peer-review
- Associations Between End-Tidal Carbon Dioxide During Pediatric Cardiopulmonary Resuscitation, Cardiopulmonary Resuscitation Quality, and SurvivalThe ICU-RESUS and Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Investigator Groups, Jan 30 2024, In: Circulation. 149, 5, p. 367-378 12 p.Research output: Contribution to journal › Article › peer-review
- Adverse outcomes and an immunosuppressed endotype in septic patients with reduced IFN-γ ELISpotBarrios, E. L., Mazer, M. B., McGonagill, P. W., Bergmann, C. B., Goodman, M. D., Gould, R. W., Rao, M., Polcz, V. E., Davis, R. J., Del Toro, D. E., Dirain, M. L. S., Dram, A., Hale, L. O., Heidarian, M., Kim, C. Y., Kucaba, T. A., Lanz, J. P., McCray, A. E., Meszaros, S., Miles, S., & 20 othersNelson, C. R., Rocha, I. L., Silva, E. E., Ungaro, R. F., Walton, A. H., Xu, J., Zeumer-Spataro, L., Drewry, A. M., Liang, M., Bible, L. E., Loftus, T. […]